Senior Independent Study Theses from 2024
Probing The Relationship Between Partial Epithelial-to-Mesenchymal-Transition and Cell Shape in Epithelial Cells, Fareeda E. Abu-Juam
Department: Biochemistry and Molecular Biology
MAP3K8 in Swine Testicular Cells Serves as an Anti-Viral Gene Against Porcine Delta Coronavirus, Brayden Beathe-Gateley
Department: Biochemistry and Molecular Biology
MAP3K8 in Swine Testicular Cells Serves as an Anti-Viral Gene Against Porcine Delta Coronavirus, Brayden Beathe-Gateley
Department: Biochemistry and Molecular Biology
Assessing Sediment Contamination Effects on CYP1A Expression in Bottom-Feeding Fishes in Northeast Ohio, Babita Biswa
Department: Biochemistry and Molecular Biology
Analyzing Polycyclic Aromatic Hydrocarbon (PAH) Concentrations in Bodies of Water Across Northeast Ohio as a Marker of Environmental Pollution, Alyssa Hope Chritz
Department: Biochemistry and Molecular Biology
Characterization of Aedes japonicus Complex in Medina, Ohio, Kaydee M. Clark
Department: Biochemistry and Molecular Biology
Characterization of Aedes japonicus Complex in Medina, Ohio, Kaydee M. Clark
Department: Biochemistry and Molecular Biology
Elucidating the Role of Reactive Oxygen Species on Dopamine đť›˝-Hydroxylase Activity and Aggregation, Shivam Dewan
Department: Biochemistry and Molecular Biology
Elucidating the Role of Reactive Oxygen Species on Dopamine β-Hydroxylase Activity and Aggregation, Shivam Dewan
Department: Biochemistry and Molecular Biology
Role of Residues R184 and W273 in 6-HNA and NADH Binding by 6-Hydroxynicotinate 3-Monooxygenase, Jack Donahue
Department: Biochemistry and Molecular Biology
Assessing Soil Recovery Dynamics in the Aftermath of the Border 32 Wildfire, Noah Fox
Department: Biochemistry and Molecular Biology; Geology
Characterization of Putative Molecule Inhibitors of MurG and Their Effectiveness in Growth Inhibition of Escherichia coli (DH5⍺), Pseudomonas frederikbergensis (36C6) and Pseudomonas chlororaphis (14B11), Spencer Gabriel
Department: Biochemistry and Molecular Biology
Structural and Kinetic Analysis of Perkinsus Marinus Creatine Kinase: Insight to Quaternary Structure Evolution of Phosphagen Kinases, Grace M. Gascoigne
Department: Biochemistry and Molecular Biology
The Impact BIRC3 has on Porcine Deltacoronavirus Infection in a Swine Testicular Cell Line, Hallie Georskey
Department: Biochemistry and Molecular Biology
Effects of Co-cultured Bacteria and Fungi on Pseudomonas protegens or Pseudomonas chlororaphis and Saccharomyces cerevisiae, Sophia Gilmore
Department: Biochemistry and Molecular Biology
Effects of Co-cultured Bacteria and Fungi on Pseudomonas protegens or Pseudomonas chlororaphis and Saccharomyces cerevisiae, Sophia A. Gilmore
Department: Biochemistry and Molecular Biology
Insights into Pyocyanin Synthesis: Unraveling the Enzymatic Interplay of PhzS and PhzM from Pseudomonas aeruginosa Boston 41501 In Vitro, Jorge Raul Gonzales Virto
Department: Biochemistry and Molecular Biology
Boolean Modeling of the Molecular Dynamics Governing the Epithelial and Endothelial Hypoxic Response, Grant Kenneth Greene
Department: Biochemistry and Molecular Biology
Biomimetic Passive Samplers to Estimate the Bioconcentration Factor of Per- and Polyfluoroalkyl Substances: Evaluation by Field Deployment in the Volta River, Ghana, Riley Hershberger
Department: Biochemistry and Molecular Biology
Elucidating the Nicotinic Acid Degradation Pathway in Bacillus Niacini: Investigating the Catabolic Function of a Flavin Monooxygenase (FMO), Domain of Unknown Function (DUF), and Hypothetical Protein (HP), Abigail A. Lyon
Department: Biochemistry and Molecular Biology
Investigating a Potential Relationship between Peroxiredoxin and Ribonucleotide Reductase in Maintaining Genomic Stability, Hieu Nguyen
Department: Biochemistry and Molecular Biology
Transmission and Polymorphisms of Culex Flavivirus in Wild-Caught Culex Mosquitoes from Cleveland, Ohio, Otilia Oita
Department: Biochemistry and Molecular Biology
Determining the Role of FMO in the Bacillus niacini Nicotinic Acid Degradation Pathway, Katherine Olson
Department: Biochemistry and Molecular Biology
Investigating Alternative Redox Partners for Thioredoxin Reductase (Trr1) of S. cerevisiae, Maria Fernanda Ossa Echeverri
Department: Biochemistry and Molecular Biology
Investigating the Redox-Active Cysteine Residues in the S. cerevisiae Mitochondrial Thioredoxin Trx3, Jenna Grace Owen
Department: Biochemistry and Molecular Biology
The Effect of Titanium on Catecholamine Enzyme; Tyrosine Hydroxylase Relationship Between Titanium Sources and Parkinson’s Disease, Seth Owens
Department: Biochemistry and Molecular Biology
Profiling the Secretome of iPSC Cardiomyocytes Using High Resolution-Mass Spectrometry for Leigh Syndrome Biomarker Discovery, Eve Painter
Department: Biochemistry and Molecular Biology
The RNA Binding Protein, Nab2, Regulates the Expression of the Extracellular Matrix Binding Domain of Dystroglycan: Implications for Intellectual Disability and Muscular Dystrophy, Allison Paschack
Department: Biochemistry and Molecular Biology
Toward Understanding How Metal Dyshomeostasis Impacts Dopamine-B-hydroxylase Activity, Mary Payne
Department: Biochemistry and Molecular Biology
Generation of a Mutant Rabbit Muscle Creatine Kinase: A Study of Protein Quaternary Structure and its Implications for Evolution, Alexander Phillips
Department: Biochemistry and Molecular Biology
Investigating Activity Loss in an Engineered Monomeric Creatine Kinase through the Lens of a Sponge-derived CK – An Exploration of Quaternary Structure Significance, Willow H. Reddish
Department: Biochemistry and Molecular Biology
Cell on the Run! Boolean Modeling of the Migrating Epithelial Cell and Induction of Mesenchymal-Epithelial Transition by OVOL2 and GRHL2, Ruth Ressler
Department: Biochemistry and Molecular Biology
Metalloporphyrin Derivatives for Photodynamic Therapy: A Comparative Study on the Synthesis and Antibacterial Activity of Copper(II) TPP-Sesamol and Copper(II) TPP-Zingerone., Rebecca I. Rogovich Champin
Department: Biochemistry and Molecular Biology
Characterization of Oxidation-Prone Cysteines in Microbial Thioredoxin Reductases, Abigail Showalter
Department: Biochemistry and Molecular Biology
Investigating Physiological Abnormalities Induced by Contaminated Aquatic Sites in Freshwater Fish Across Northeast Ohio, Kyle Stringer
Department: Biochemistry and Molecular Biology
Cytotoxicity of Porphyrin-Based Photosensitizers on Staphylococcus Aureus, Makeda Tekelmichael
Department: Biochemistry and Molecular Biology
Cytotoxicity of Porphyrin-Based Photosensitizers on Staphylococcus Aureus Cells, Makeda Tekelmichael
Department: Biochemistry and Molecular Biology
Investigating the Interplay Between RNR, Tsa1, and the Thioredoxin System and Their Effect on Cell Cycle Regulation in Saccharomyces cerevisiae, Malaika Webb
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2023
Exploring the Binding Multiplicity, Mode of Inhibition and Communication Between NADH Binding Sites on 6- Hydroxynicotinate 3-monooxygenase (NicC), Eric Senanu Adadevoh Mr.
Department: Biochemistry and Molecular Biology
Porphyrin Based Photosensitizing Agents: Comparative Study On The Effects Of TPP-sesamol and TPP-zingerone On Yeast Cells, Edwina Akonor
Department: Biochemistry and Molecular Biology
Measurement & Analysis of Pesticide Biotransformation Products in Ohio Precipitation Samples, Lily Anderson
Department: Biochemistry and Molecular Biology
Interrogation of a Conserved Overlap Between Cofactor and Substrate Binding Domains to Facilitate Crosstalk-Induced Conformational Changes in Class A Flavin Monooxygenases: A Case Study of 6-Hydroxynicotinate-3-Monooxygenase, Sam L. Belsky
Department: Biochemistry and Molecular Biology
Analysis of P. aeruginosa Antibiotic Resistance Development at Variable Ciprofloxacin Growth Concentrations In Vitro and In Vivo Using C. elegans Host, Daniel William Bohl
Department: Biochemistry and Molecular Biology
Metabolomics of iPSC-Derived Cardiomyocyte Secretions for Biomarker Discovery in Leigh Syndrome, Amber J. Dinchman
Department: Biochemistry and Molecular Biology
Metabolomics of iPSC-derived Cardiomyocyte Secretions for Biomarker Discovery in Leigh Syndrome, Amber J. Dinchman
Department: Biochemistry and Molecular Biology
Exploring Novel Redox Partners and Properties of the Thioredoxin Reductase Trr1 from Saccharomyces cerevisiae, To Uyen Do
Department: Biochemistry and Molecular Biology
Polycyclic Aromatic Hydrocarbon (PAH) Pollution Analysis and Ameiurus Nebulosus Gene Expression Can Predict Environmental Health, Naomi Fernandes
Department: Biochemistry and Molecular Biology
Liver Tumors in Beckwith Wiedemann Syndrome: Can Alpha-Fetoprotein Levels Distinguish Benign from Malignant Tumors?, Sena Houessou-Adin
Department: Biochemistry and Molecular Biology
Liver Tumors in Beckwith Wiedemann Syndrome: Can Alpha-Fetoprotein Levels Distinguish Benign from Malignant Tumors?, Sena Disewari Houessou-Adin
Department: Biochemistry and Molecular Biology
Creation of Dimeric Perkinsus Marinus Creatine Kinase Through Site-Directed Mutagenesis: Insight into Phosphagen Kinase Quaternary Structure Evolution, Kyungjoo Kim
Department: Biochemistry and Molecular Biology
Investigation Of SI And PC1 Bacteriophages' Putative Genomic Identities And Infection Methods On Phage Resistant Pseudomonas Chloraphis, May M. Le
Department: Biochemistry and Molecular Biology; Biology
Metabolomics to Predict the Onset of Cardiomyopathy in Patients with Propionic Acidemia, Riley Thomas McErlean
Department: Biochemistry and Molecular Biology
A Polynucleotide Biosensor for the Prostate Cancer Specific Biomarker PCA3, Christopher Andrew Meyer
Department: Biochemistry and Molecular Biology
A Polynucleotide Biosensor for the Prostate Cancer Specific Biomarker PCA3, Christopher Andrew Meyer
Department: Biochemistry and Molecular Biology
A Polynucleotide Biosensor for the Prostate Cancer Specific Biomarker PCA3, Jessica Krystal Meyer
Department: Biochemistry and Molecular Biology
Structural Stability of Bovine Serum Albumin upon Adsorption to SOMS Measured by FT-IR, Kylie M. Schmitz
Department: Biochemistry and Molecular Biology
Toward a Comprehensive Framework for Investigating Copper Dyshomeostasis: The Role of His-Tag Modularity and Alternative Expression Systems in Evaluating Dopamine β-Hydroxylase, Zoë Lee Semersky
Department: Biochemistry and Molecular Biology
Immobilization of Transferrin in Swellable Organically Modified Silica for Remediation of Heavy Metal Ions, Shiropa Shahreen
Department: Biochemistry and Molecular Biology
Investigation of Splicing Changes in dNab2 Knockdown Drosophila Neurons, Katherine J. Shelmidine
Department: Biochemistry and Molecular Biology
Conservation of Dynamic Modularity in Biological Network Modeling: Modular Boolean Model of Cell Cycle Regulation in Saccharomyces cerevisiae, Caitlin Strassburg
Department: Biochemistry and Molecular Biology; Mathematics
Identifying Potential Redox Partners of the Yeast Mitochondrial Thioredoxin, Griffin G. Suppa
Department: Biochemistry and Molecular Biology
Cytochrome p450 1A Oxidation of Pollutant Benzo(a)pyrene's Genetic Effect on Ameiurus nebulosus’ p53 and MDM2 Genomic Region, Breanna Watkins
Department: Biochemistry and Molecular Biology
Determining The Crystal Structure of The Staphylococcus Aureus MurG Enzyme, Patrick Thomas Wood
Department: Biochemistry and Molecular Biology
Identification of a Putative Binding Mechanism for the Reducing Substrate of 6-Hydroxynicotinate 3-Monooxygenase, Takoda T. Zuehlke
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2022
Phenotypic Rescue Of Key Social Behaviors In M. Xanthus By The Desulfotalea Psychrophila Arginine Kinase, Nathaniel J. Arday
Department: Biochemistry and Molecular Biology
Role Of Tight Binding In Negative Cooperativity In The Dimeric Mitochondrial Taurocyamine Kinase From Arenicola Brasiliensis, Robert M. Beal
Department: Biochemistry and Molecular Biology
Identification And Detection Of Biomarkers Of Dilated Cardiomyopathy In A Cohort Of Amish Patients With Propionic Acidemia Using High Resolution Mass Spectrometry, Alexa Nicole Bencic
Department: Biochemistry and Molecular Biology
To Clean Or Not To Clean: Exploring The Ability Of Biocidal Compounds To Induce Physiological Changes In Bacteria That May Increase The Spread Of Antibiotic Resistance Genes, Kayla R. Bertholf
Department: Biochemistry and Molecular Biology
Boolean Model Of Mesenchymal Cell'S Resistance To Chromosomal Senescence, Arnav Bhatnagar
Department: Biochemistry and Molecular Biology
Synthesis, Characterization, And Biological Activity Of Silver (I) Fatty Acid Complexes Against Candida Albicans, Macy Faith Bischoff
Department: Biochemistry and Molecular Biology
The Seven Deadly Pathways: A Boolean Model Of Yeast Apoptosis In Response To Reactive Oxygen Species, DNA Damage, And Salt, Andrea Brown
Department: Biochemistry and Molecular Biology
Molecular Recognition Within The Es Complex: A Mechanistic Investigation To Discern How 6-Hydroxynicotinate-3-Monooxygenase (Nicc) Distinguishes Between Substrate Analogues When Enhancing Its Rate Of Nadh Oxidation, Joel K. Brown
Department: Biochemistry and Molecular Biology
“It’S Not Just A Phage, Mom”: An Examination Of Antibiotic Resistance In Pseudomonas Aeruginosa In Response To Bacteriophage Treatment, Kirsten N. Buchan
Department: Biochemistry and Molecular Biology
Effects Of Xenobiotic Pollution On Histopathological Alterations And Cyp1A Expression On Brown Bullhead (Ameiurus Nebulosus) In Wooster, OH, Madison A. Crucs
Department: Biochemistry and Molecular Biology
The Virome Of Aedes Japonicus And Culex Spp., Collected In Wooster, Oh, Usa, Alexander R. DeLong
Department: Biochemistry and Molecular Biology
Biochemical Analysis Of The Myxococcus Fulvus 124B02 Arginine Kinase, Krista L. English
Department: Biochemistry and Molecular Biology
Analysis Of The Antimicrobial Activity Of The Novel Chemotherapeutic Drug, Tpp1, Against Pseudomonas Aeruginosa And The Hydrogel Delivery Of Water-Soluble Antimicrobial Compounds, Alex Gasper
Department: Biochemistry and Molecular Biology
Advances In Characterizing The Gene-Encoded Subunits That Compose The Nicotinate Dehydrogenase And 6-Hydroxynicotinate Dehydrogenase Enzyme Complexes Within The Bacillus Niacini Nicotinic Acid Degradation Pathway, Emilee R. Haines
Department: Biochemistry and Molecular Biology
Investigating Substrate Specificity For 6-Hydroxynicotinate 3- Monooxygenase (Nicc) With Alternative Substrates: Consequences To Catalysis Of Replacing Or Removing The Ring Nitrogen, May Zin Hlaing
Department: Biochemistry and Molecular Biology
Characterization Of A Potential Novel Redox Partner In S. Cerevisiae Mitochondrial Disulfide Relay System And In Silico Elucidating Its Essentiality, Thinh Huynh
Department: Biochemistry and Molecular Biology
The Influence Of Silver (I) Carboxylate Ligand Structure On Antimicrobial Activity In Pseudomonas Aeruginosa, Kylie E. Keller
Department: Biochemistry and Molecular Biology
Synthesis, Characterization, And Antimicrobial Activity Of Folic Acid And Glutamic Acid Derived Silver (I) Compounds Against Pseudomonas Aeruginosa, Benjamin James Kennedy
Department: Biochemistry and Molecular Biology
Advances In The Elucidation Of The Nicotinic Acid Degradation Pathway In Bacillus Niacini: Proof Of Formation Of The Trihydroxypyridine Intermediate And The Characterization Of An Fmn-Dependent Flavoprotein Of Unknown Function, Sai Kwan Khal
Department: Biochemistry and Molecular Biology
Examining The Role Of Arginine Kinase In The Social And Physiological Processes Of Myxococcus Xanthus, Lillian R. MacLean
Department: Biochemistry and Molecular Biology
Following The Lead: Impact Of Soil Amendments On Lead Toxicity To Tomato, Alicia McElwee
Department: Biochemistry and Molecular Biology
The Effect Of Adipokinetic Hormone (AKH) On Fecundity Of Aedes Aegypti Mosquitoes., A'Janay C. Nicholson
Department: Biochemistry and Molecular Biology
Examining The Effects Of Angiotensin I-Converting Enzyme On The Fecundity Of Female Aedes Aegypti Mosquitoes, Daphne Lynn Pate
Department: Biochemistry and Molecular Biology
Allelochemical In Situ Evaluation Of A Swellable Organically Modified Silica Based Sampler Using Lc-Ms/Qtof, Damien M. Sausville
Department: Biochemistry and Molecular Biology
Investigating Whether The Rna Binding Protein Nab2 Regulates Tau Mrna Levels In A Fly Model Of Neurodegeneration, Emma Grace Schwinne
Department: Biochemistry and Molecular Biology
Boolean Modeling Of The Interactions Between Inflammation, Hypoxia, And The Epithelial-Mesenchymal Transition (Emt), Ian Zonfa
Department: Biochemistry and Molecular Biology
Characterization Of The Natural Antibiotic Activity Of Pseudomonas Environmental Isolates, Harrison Zwolshen
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2021
The Female Perspective: An Investigation Into How the Reconstruction and Efficacy of a Gynecological Fertility Recipe Unveils Female Voice in the Hippocratic Corpus, Randa Elie Abboud
Department: Biochemistry and Molecular Biology; Classical Studies; History
Maternal and Infant Factors That Influence Infant Microbiome Composition and Microbial Fucose Utilization, Grace E. Adkins
Department: Biochemistry and Molecular Biology
Investigating the Effects of the Phone a STEM Professional Assignment on STEM Students’ Sense of Belonging, Career Confidence, and Career Awareness, Kyla M. Babics
Department: Biochemistry and Molecular Biology
Simulating Mammalian Liver Homeostasis and the Impact of Senescence, Stuart Ryan Ball
Department: Biochemistry and Molecular Biology
Reconstitution of Hydroxylation Activity of Recombinant NDH and 6-HDH Complexes from Bacillus niacini, Luke Borgelt
Department: Biochemistry and Molecular Biology
Searching for Novel Redox Partners of the Mitochondrial Protein Erv1, Camryn A. Bragg
Department: Biochemistry and Molecular Biology
Investigation of the Metabolic Role of Triosephosphate Isomerase (TPI) in the Physiological function of Myxococcus xanthus, Sienna F. Carr
Department: Biochemistry and Molecular Biology
Elucidating Phosphagen Kinase Evolution through the Identification of Substrate Specific Arginine Kinases and Taurocyamine Kinase within Platyhelminthes, Emmalee Cooke
Department: Biochemistry and Molecular Biology
Investigating the Efficacy of RNAi for Use in the Study of Caenorhabditis elegans Arginine Kinase, Evan Thomas Faxon
Department: Biochemistry and Molecular Biology