Cell on the Run! Boolean Modeling of the Migrating Epithelial Cell and Induction of Mesenchymal-Epithelial Transition by OVOL2 and GRHL2

Authors

Ruth Ressler, The College of WoosterFollow

Advisor

Regan, Erzsebet

Department

Biochemistry and Molecular Biology

Recommended Citation

Ressler, Ruth, "Cell on the Run! Boolean Modeling of the Migrating Epithelial Cell and Induction of Mesenchymal-Epithelial Transition by OVOL2 and GRHL2" (2024). Senior Independent Study Theses. Paper 10921.
https://openworks.wooster.edu/independentstudy/10921

Disciplines

Biomechanics | Biophysics | Cancer Biology | Cell Anatomy | Cell Biology | Cellular and Molecular Physiology | Computational Biology | Dynamical Systems | Molecular Biology | Molecular Genetics | Systems Biology

Keywords

EMT, MET, cancer cell stemness, OVOL2, GRHL2, hybrid E/M, epithelial, mesenchymal, biomechanics, mechanotransduction, migration, invasion, metastasis, tumorigenesis, phenotypic plasticity, contact inhibition of proliferation, anoikis, mechanosensitivity, matrix stiffness, boolean modeling, boolean logic

Publication Date

2024

Degree Granted

Bachelor of Arts

Document Type

Senior Independent Study Thesis