Senior Independent Study Theses from 2014
Pertusiss, Pellagra, and Poverty: A Historical and Scientific Analysis of Whooping Cough's Associations with Poverty and Pellagra, and the Nicotinate Degradation Pathway in Bordetella Pertussis, Jacob Sprano
Department: Biochemistry and Molecular Biology; History
Developing an Effective Vaccine for Porcine Reproductive and Respiratory Virus (PRRSV), John M. Thompson
Department: Biochemistry and Molecular Biology
Disrupting Dimer Formation in the Baker’s Yeast Alkyl Hydroperoxide Reductase 1 (Ahp1), Susmit Tripathi
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2013
Characterization of Two Contiguous-Dimer Taurocyamine Kinases From the Parasitic Trematodes Schistosoma Japonicum and Clonorchis Sinensis, Brittany Begres
Department: Biochemistry and Molecular Biology
A Preliminary Analysis of the Differences in Cyclosporin a Resistance Between Amino Acid Residues P538 and P540 of the Hepatitis C Polymerase, Alexandra Kuzmishin
Department: Biochemistry and Molecular Biology
Protective Role of the Yeast Peroxiredoxin Tsa1 Against Electrophile-Mediated Stress, Andrew Lamade
Department: Biochemistry and Molecular Biology
Size Selective Dna Purification Using Swellable Organically Modified Silica, Brian Alexander Lupish
Department: Biochemistry and Molecular Biology
Shedding Light on the DEAD: Preliminary Investigation Into Dbp6, a DEAD-box Protein Required For Ribosome Assembly, Kari Martyniak
Department: Biochemistry and Molecular Biology
Investigating Cis-Elements of Microtubule-Associated Protein Tau's 3'-Untranslated Region, Daniel Montagna
Department: Biochemistry and Molecular Biology
Investigation of Functional Roles For Thioredoxins in Protecting Against Reversible Electrophile Induced Protein Damage in Saccharomyces Cerevisiae, Wesley J. Murphy
Department: Biochemistry and Molecular Biology
Characterization of a Creatine Kinase Enzyme From Cryptosporidium Muris, Paige Piper
Department: Biochemistry and Molecular Biology
Protein Cross-Linking As a Mechanism of Cytotoxicity For Bifunctional Electrophiles, Nikolai Radzinski
Department: Biochemistry and Molecular Biology
Assessing the Ability of Environmental Microbes to Catabolically Degrade the Antidepressant Venlafaxine (Effexor®), Kathryn Clare Sullivan
Department: Biochemistry and Molecular Biology
The Impact of Formate on the Physiology of Campylobacter jejuni, Michael T. Terribile
Department: Biochemistry and Molecular Biology; Neuroscience
Characterizing the Role of 2-Oh-Pca in P. Chlororaphis Pathogenesis, Abigail Toothman
Department: Biochemistry and Molecular Biology
Protein Drug Delivery Using Swellable Organically Modified Silica, Stephen Wanner
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2012
Glycogen Synthase Kinase-3 Regulates DNA Methylation Near Genes Implicated in Bipolar Disorder, Colleen Marie Bartman
Department: Biochemistry and Molecular Biology
Arginine Kinase of Myxococcus Xanthus Influences Development in a Manner Dependent on the Conditions of Development, Thomas Bohl
Department: Biochemistry and Molecular Biology
Influence of the Protein Cross-Linker Diethyl Acetylenedicarboxylate on 20S Core Particle Degradation of Candidates for the 26S Proteasome, TeQuion M. Brookins
Department: Biochemistry and Molecular Biology
Alterations in the Activity of the Yeast Peroxidase Tsa1 Upon Modification By Alkylating Agents, Haley A. Brown
Department: Biochemistry and Molecular Biology
Isolation of Bacterial Strains in Wastewater Sludge Capable of Degradation of Sertraline, Venlafaxine and Triclocarban, Jonathan Fox
Department: Biochemistry and Molecular Biology
Burdock Leaves: Cellular and Antimicrobial Effects in Burn Wound Treatment, Kelsie L. Herring
Department: Biochemistry and Molecular Biology
Evolutionary Study of the Phosphagen Kinase Enzyme Family Probing Substrate Specificity and Cooperativity in Software Derived Ancestral Proteins, Eric Johnson
Department: Biochemistry and Molecular Biology
Investigation of the Potential Role of 6-Hydroxynicotinate-3-Monooxygenase in the Modulation of Virulence in Bordetella Pertussis, Samantha Justice
Department: Biochemistry and Molecular Biology
Progress Towards the Characterization of a Novel Substrate-Analog Inhibitor of Udp-3-O-(R-3-Hydroxymyristoyl)-N-Acetylglucosamine Deacetylase, Emily Christine Linville
Department: Biochemistry and Molecular Biology
Investigation Into the Catalytic Mechanism of Maleamate Amidohydrolase (NicF) from Bordetella Bronchiseptica RB50, Jeffrey Noel
Department: Biochemistry and Molecular Biology
Generation of Thioredoxin 1 and Thioredoxin 2 Mutants in S. Cerevisiae and a Philosophical Investigation of the Ethical Implications of Human Genetic Engineering, Logan D. Pry
Department: Biochemistry and Molecular Biology; Philosophy
Entrapment and Determination of Lipase Embedded in Swellable Organosilica, Modeling Particle Aggregation and Aging of Colloidal Sol-Gels, Kemar Reid
Department: Biochemistry and Molecular Biology
Probing the Role Cysteine-150 in Maleamate Amidohydrolase (NicF) Catalysis From Bordetella Bronchiseptica RB50 By Site-Directed Mutagenesis, Nicholas Spittle
Department: Biochemistry and Molecular Biology
Identification and Characterization of HAP1, a YAP1 Homologue, in the Fungus Histoplasma Capsulatum, Blain Tesfaye Fente
Department: Biochemistry and Molecular Biology
Computational Profiling and Identification of the 3' Untranslated Region Within Paramecium Tetraurela, Tristan Vrolijk
Department: Biochemistry and Molecular Biology; Computer Science
Mapping Polyprotein Cleavage Sites in the R78 Region of Maize Chlorotic Dwarf Virus, Yujing Zhao
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2011
Investigating the Localization and Function of the Prodomain of Neuronal Interleukin-16 on N1E-115 Cells, Cassondra Agozzino
Department: Biochemistry and Molecular Biology
Influence of Proteasome Inhibition on the Baker's Yeast Transcription Factor Yap1p Following Its Activation By Organic Electrophiles, Omar Atassi
Department: Biochemistry and Molecular Biology
Investigation of a Putative Arginine Kinase From Desulfobacterium Autotrophicum: Evolutionary Implications For the Bacterial Arginine Kinases, Christopher DeMoll
Department: Biochemistry and Molecular Biology
Investigating the Role of Threonine-58 in Creatine Kinase Activity and Active Site Communication, Dmytri Eck
Department: Biochemistry and Molecular Biology
Developing a Mechanistic Proposal For 2,5-Dihydroxypyridine-5,6-Dioxygenase (NicX) from Bordetella Bronchiseptica, Matthew Henke
Department: Biochemistry and Molecular Biology
A Study of the Structure/Function Relationship of NicF in the Bordetella Bronshiseptica Nicotinic Acid Degradation Pathway, Roger Klein
Department: Biochemistry and Molecular Biology
Solute Induced Delivery of Small Molecules and Biologics Using Swellable Organically Modified Silicas, Benjamin Leiden
Department: Biochemistry and Molecular Biology
Method Development For Quantitative Analysis of Prostanoids and Isoprostanes in Human Serum to Investigate the Molecular Basis of Aspirin Resistance, Mary Kate Lockhart
Department: Biochemistry and Molecular Biology
Organosilica-Polymer Composit Materials For Capture and Release of DNA for Forensic Application, Laszio Marcze
Department: Biochemistry and Molecular Biology
Thermodynamic and Infrared Spectroscopic Study of the Excited State Intramolecular Charge Transfer of 4-Aminobenzoic Acid and 4-Dimethylaminobenzoic Acid, Zachery Matesich
Department: Biochemistry and Molecular Biology
Analysis and Characterization of Siphonosoma Cumanense HTK: Evolutionary Implications, Robert Mayer Jr
Department: Biochemistry and Molecular Biology
The Characterization of a Hybrid Histidine Kinase in the Pathogenic Dimorphic Fungus Histoplasma Capsulatum, Mary Rebecca Moreci
Department: Biochemistry and Molecular Biology
An Investigation of the Ability of Pseudomonas Fluorescens to Degrade the Antidepressent Sertraline (Zoloft®), Brad Palanski
Department: Biochemistry and Molecular Biology
Identification of Genes That Provide Cellular Protection Against a Thiol Cross-Linking Agent in Saccharomyces Cerevisiae, Chelsea Stamm
Department: Biochemistry and Molecular Biology
Characterization of Siderophore Transporters Abc1 and Mfs1 in Histoplasma Capsulatum Pathology, Emily Weitz
Department: Biochemistry and Molecular Biology
Evidence of Subfunctionalization in the Calcineurin Gene Family in Paramecium Tetraurelia, Jordan Welker
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2010
Viral Pathogen Removal From Water Using Swellable Organically Modified Silica, Emily J. Barth
Department: Biochemistry and Molecular Biology
Differential Gene Expression of H. Bacteriophora TTO1 in Response to Heat Stress, Marc Christian
Department: Biochemistry and Molecular Biology; Mathematics
Identifying Genes Required For Growth in Histoplasma Capsulatum Under Osmotic Stress Conditions, Angela Grass
Department: Biochemistry and Molecular Biology
Chemical Analysis of Materials Used to Create the Paint Found on the College of Wooster's Egyptian Coffin, Kimberly Anne Krall
Department: Biochemistry and Molecular Biology
Capacity For Microbial Biomass to Be Used in Biological Control to Manage Plant Pathogen Growth: Advancement of Pseudomonas Flourescens Strain Wayne1R As a Biocontrol Agent Through Identification of Novel Biocontrol Genes, Seth A. Maurer
Department: Biochemistry and Molecular Biology
Expression and Characterization of Phytophthora Sojae Phosphagen Kinases, Allyson Kaitlin Palmer
Department: Biochemistry and Molecular Biology
Nad Catabolism: Identification of a 6-Hydroxynicotinate 3-Monooxygenase in Bordetella Bronchiseptica, Ryan Wilson Story
Department: Biochemistry and Molecular Biology
Effects of Neuregulin-1 on Long Term Potentiation in Cerebellar Granule Cells in Vitro, Andrew Trembath
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2009
Investigating the Use of Oral Creatine Supplementation As a Means of Treatment For the Symptoms of Fibromyalgia Syndrome, Valerie Marie Andrus
Department: Biochemistry and Molecular Biology
Using GFP Fusion Proteins to Screen For the Subcellular Localization of Phytophthora Infestans RXLR Effectors in Host Cells, Samantha Jo Armintrout
Department: Biochemistry and Molecular Biology
Investigating the Role of the IQ67 Domain in the Interaction Between SUN and Calmodulin: An Endeavor Into the Treacherous World of Protein Expression Via Escherichia Coli, Stephanie Louise Edmisson
Department: Biochemistry and Molecular Biology
Microbial Degradation of Triclosan Within Wastewater Treatment Plants, Sarah Gollwitzer
Department: Biochemistry and Molecular Biology
Characterizing the Role and Function of Two Hybrid Histidine Kinases in Histoplasma Capsulatum, Daniel W. Grangaard
Department: Biochemistry and Molecular Biology
DNA Geometry and Its Biological Significance, Lorna Johnston
Department: Biochemistry and Molecular Biology; Mathematics
Using Computational Genomics to Develop a General Gene Model For the Plant Pathogen Phytophthora Infestans, Michael Kwan
Department: Biochemistry and Molecular Biology
A 31P-NMR Study to Determine the Structure of Nanodispersions in Contrast to the Standard Bi-Layer of Liposomes, Marcus T. Liotta
Department: Biochemistry and Molecular Biology
Fusing Interstices: Exploring the Relationship Between Science and Religion in Theory, in Particular Relgious Scientists and in Self, Elise A.G. Meyers
Department: Biochemistry and Molecular Biology; Religious Studies
Characterization of a Putative Monooxygenase Involved in Nad Catabolism, Theodore Carlton Moore, III
Department: Biochemistry and Molecular Biology
Don't Fret the Exchange Rate: the Study of Subunit Exchange Between Oligometric Complexes of ZmHsp17.0-CII Using Fluorescence Resonance Energy Transfer, Chris T. Nau
Department: Biochemistry and Molecular Biology
Investigating the Difference Between Archaeal and Eukaryal Nucleosomal Exchange Using Fluorescence Resonance Energy Transfer, Brittany L. Pitrone
Department: Biochemistry and Molecular Biology
Invitro Inhibition of Matrix Metalloproteinase 9 in Human Breast Cancer Cells, Luke A. Stetzik
Department: Biochemistry and Molecular Biology
Increased Glucagon-Like Peptide-1 (GLP-1) in Type II Diabetics: Results of a High-Fiber Plant-Based Diet, Elizabeth Bailey Wakefield
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2008
Purification of Protected Cyclohexyl Phospho Carbobenzyloxy-L-Serine Benzyl Ester and the Synthesis and Purification of Deprotected Cyclohexyl Phospho-L-Serine Which Is a Potential Analog of Phosphatidylserine, Nicholas Jay Amato
Department: Biochemistry and Molecular Biology
An Investigation Into the Role of Creatine in Muscle Toxicity Associated With Statin-Use, Jason Bowie
Department: Biochemistry and Molecular Biology
Investigating the Role of the C-Terminal Domain in McsB, a Structurally Unique Tyrosine Kinase Found in Bacillus subtilis, James Graham
Department: Biochemistry and Molecular Biology
Regulation of the Activation of Heat Shock Factor 1: One Mechanism of Glutamine-Mediated Protection During Cellular Stress, Sarah Haserodt
Department: Biochemistry and Molecular Biology
Antimicrobial Effects of the Organosulfur Compounds Diallyl Monosulphide, Diallyl Disulphide, and Kiallyl Trisulphide Found in Allium Sativum Against Planktonic Methicillin-Resistant Staphylococcus Aureus (Mrsa) and Mrsa Biofilms, Kelly Knapp
Department: Biochemistry and Molecular Biology
Evolution of Cooperativity in the Phosphagen Kinase Family, Marisa P. McGinley
Department: Biochemistry and Molecular Biology
Converting a Monomeric Arginine Kinase to a Dimer Through Directed Evolution, Warren C. Swegal
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2007
Prevalence of Sodium Chlorate Resistant Escherichia Coli O157:H7 and a Potential Resistance Mechanism, Alicia Cattaneo
Department: Biochemistry and Molecular Biology
Investigation into a Nonlinear Cascade Model for Describing the Genetic Basis of the Neurofibromatosis Type 1 Phenotype Using a Murine Embryonic Fibroblast Model, Joshua T. Graber
Department: Biochemistry and Molecular Biology
Investigation of the Interaction Between Neuronal Interleukin-16 and An A-Type Potassium Channel Subunit, Hannah Patia Leahy
Department: Biochemistry and Molecular Biology
Investigation of Creatine to Creatinine Ratios in Fibromyalgia, Severin Pouly
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2006
Investigation of the Creatine/Creatinine Ratio in Serum and Urine: A Potential Link to Muscle Pain Associated with Statin Use, J. Matt Craig
Department: Biochemistry and Molecular Biology
Triclosan and Antibiotic Cross-Resistance in Salmonella Enterica Serotype Typhimurium, Rebecca Danner
Department: Biochemistry and Molecular Biology
Investigation of Bioactivity of Seed Extracts From the Apiaceae (Umbelliferae) Plant Family, Ronny Ewanek
Department: Biochemistry and Molecular Biology
Apoptotic Cascades As Possible Targets For Inhibiting Apoptosis in Huntington's Disease, Lindsay Pattison
Department: Biochemistry and Molecular Biology
Investigating the Effects of Different Diets on the Microbial Communities and Cellular Morphologies Within the Intestinal Tract of Broiler Chickens and Turkey Poults, Rebecca Connelly Prada
Department: Biochemistry and Molecular Biology
Investigating the Synthesis of Siloxymethyl Glucuronide: Progress in the Synthesis of C-Linked Retinoyl β-Glucuronide, Kathryn M. Torrey
Department: Biochemistry and Molecular Biology
Senior Independent Study Theses from 2005
Determining Variations in Glyphosate Susceptibility Among Velvetleaf (Abutilon Theophrasti, Malvaceae) Accessions, Jala J. Daniel
Department: Biochemistry and Molecular Biology
Expression and Purification of the Small Heat Shock Protein Zmhsp17.8-CII, Melisa L. Kundracik
Department: Biochemistry and Molecular Biology
Assessing the Diversity of A-Genotype Strain of 2,4-Diacetylphoraglucinol-Producing Pseudomonas Fluorescens Using Suppressive Subtraction Hybridization, Adam E. Osborne
Department: Biochemistry and Molecular Biology