Abstract

This paper thoroughly covers aspects of the highly contagious Canine Distemper Virus (CDV) which affects many different species including felids and other non-canid animals. CDV is a deadly RNA virus in the morbillivirus genus that’s related to the measles virus and rinderpest virus. While CDV does affect domesticated animals like dogs and ferrets, it has a wide scope of afflicted species that bring concerns for wildlife and endangered species; including conservation issues and preventing further spread of the virus. We will examine three aspects of CDV infection: Neurological, Cross-Species infection, and Vaccinations as well as Antiviral research. Recently there have been heightened concerns about the transmission of CDV to humans, as has been seen in our closest non-human primate relatives like Rhesus monkeys. While the currently available vaccines are effective in limiting the spread of CDV, there is no direct treatment for infected animals and most afflicted animals end up dead, especially once the virus reaches the brain. The purpose of this review is to bring attention to the severity of the virus and the need for a readily available antiviral treatment.

Advisor

Brandley, Nicholas

Department

Biology

Disciplines

Veterinary Infectious Diseases | Veterinary Medicine | Veterinary Microbiology and Immunobiology | Veterinary Pathology and Pathobiology | Veterinary Preventive Medicine, Epidemiology, and Public Health

Keywords

Canine Distemper, Canine Distemper Virus, CDV, Review, Antiviral, Neurological, Species Jump

Publication Date

2025

Degree Granted

Bachelor of Arts

Document Type

Senior Independent Study Thesis

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Available for download on Monday, July 08, 2030

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