The full text of Senior Independent Study Theses submitted during and after 2012 are available to download only by College of Wooster users. Unless listed as an exemplar, all other theses are restricted.

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Senior Independent Study Theses from 2004

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Fabrication of Microfludic Capillary Electrophoresis Devices on Glass Substrates, Aaron Vannucci
Department: Chemistry

Senior Independent Study Theses from 2003

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A Theoretical Investigation of the Site Preference of Atomic Oxygen Chemisorption on fcc (111) and hcp (0001) Surfaces of Selected Transition Metals, Yan Min Aung
Department: Chemistry

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A Computational Study into Nitrogen-Inversion of N-benzyl-2-methylaziridine, Amanda Bain
Department: Chemistry

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Temperature Effects on Substrate Binding and Activation by Creatine Kinase, Jennifer Ann Bayuk
Department: Chemistry

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Catalytic Reduction of Ketones Using [FeH6] [Mg(t-Bu0)]4, Carson E. Bennett
Department: Chemistry

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The Elucidation of the Reaction Mechanism of the Nucleophilic Ring Opening of an Aziridium Ion at the Monosubstituted Center, Dorottya Blaho
Department: Chemistry

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The Computational Modeling of Oxygen Chemisorption on Cu(110), Christie L. Boost
Department: Chemistry

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Attempted Reverse Phase High Performance Liquid Chemotagrophy Separation with Acetonitrile for the Minor Product in the N-benzyl-N-methyl-2-methylaziridinium Triflate Formation Reaction and Characterization of the Eluted Compounds, Jaime Bryk
Department: Chemistry

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Preliminary Evidence for RNA Interference in the Plant Pathogen Phytophthora infestans, Sherrie Divito
Department: Chemistry

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Screening for Active Creatine Kinase, Jennifer Dlwgosh
Department: Chemistry

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The Synthesis and Characterization of the Hydridosilsesquioxanes, Matthew Dreyfus
Department: Chemistry

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The Evolution of Phosphagen Kinases: Changing the Substrate Specificity of Creatine Kinase to Glycocyamine Using Site-Directed Mutagenesis, Michael Jourden
Department: Chemistry

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Synthesis and Characterization of 2-Nitrobenzylidenes, Seth Kerechanin
Department: Chemistry

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Development of a Chemical Sensor for TNT Based on a Molecularly Imprinted Sol-Gel Material, Julie Lloyd
Department: Chemistry

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Development of a Quantitative Protocol Using 31P NMR Spectroscopy to Study the Reaction of the Spontaneous Phosphoryl Transfer from MgATP to Creatine, Virginia Miraldi
Department: Chemistry

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Planar Integrated Optical Waveguides as a Platform for Chemical Sensors Utilizing Solvatochromic Dyes, William Schumacher
Department: Chemistry

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The Expression and Purification of a Caenorhabditis elegans Arginine Kinase, Tabetha Shelly
Department: Chemistry

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The Development of the Ion Selective Electrode Methodology for the Analysis of Cyclohexyl Phosphoserine Small Molecule Analogs, Jeffrey Spraggins II
Department: Chemistry

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The Chiral Reduction of Acetophenone Methylimine Using [FeH6] [Mg2(BIMO)]2, Jonathan Spragg
Department: Chemistry

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The Synthesis of Novel Beta-Amino Nitriles via The Aziridinium Cyanide Reaction, Kurt Sudeall
Department: Chemistry

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Theoretical Comparison of Reaction Pathways of the Catalytic Oxidation of CO on Pt(111), Anne Zimmerman
Department: Chemistry

Senior Independent Study Theses from 2002

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The Chaperone Activity and Oligomerization of Small Heat Shock Proteins form Zea mays, Lisa Lucas
Department: Chemistry

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The Synthesis of Cyclohexanediol Biphosphate and Cis-Cyclohexyl (Bis)diphenylphosphate for the Process of Developing a Phospholipid Analog of Phosphatidylserine, John Peterson
Department: Chemistry

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Expression and Purification of SeMetHSP18-9 in Preparation for Crystallization and the Crystallization of sHSHP18-1, Emily Rainey
Department: Chemistry

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The Chemisorption of Carbon Monoxide on Late Transition Metal Alloyed Surfaces, Jeb Ray
Department: Chemistry

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Inducible Antibiotic Resistance in Escherichia coli K12: The Role of Motility, Abhishek Saharia
Department: Chemistry; Biology

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Synthesis of Fluorescence Resonance Energy Transfer Probe for Measurement of Sol-Gel Aging, Alvira Shah
Department: Chemistry

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The Computational Analysis of the Relative Stabilities of the Oligomers and Isomers of Hydridosilsesquioxanes, Jocelyn Somers
Department: Chemistry

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The Synthesis of Cyclohexyl CBZ-L-Ser-Bzl Phosphodiester as a Synthetic Precursor to a Phospholipid Analog of Phosphatidylserine, Jennifer Sorrells
Department: Chemistry

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A Computational Approach to the Modeling of CO Chemisorption on Pure and Alloyed Transition Metal Surfaces, Shawn Sullivan
Department: Chemistry

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The Siloxymethylation of beta-D-Glucose Pentaacetate: Progress Towards the Synthesis of the C-linked Retinoyl beta-Glucuronide, Tracy Ward
Department: Chemistry

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A Theoretical Study of Carbonyl Chemisorption on Platinum and Platinum Titanium Surfaces, Matthew Wellons
Department: Chemistry

Senior Independent Study Theses from 2001

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Use of Infrared Spectroscopy to Detect Disease, Jennifer Elisabeth Becker
Department: Chemistry

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The Determination of Atrazine in Surface Waters of Eastern Wayne County, Ohio, Eric Scott Bodle
Department: Chemistry

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Tools of the Second Chemical Revolution: Instrumental History and Design, Christopher J. Brubaker
Department: Chemistry

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Synthesis of an Active Monomer of Rabbit Muscle Creatine Kinase Using Site-Directed Mutagenesis, Julia Cox
Department: Chemistry

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St. John's Wort: Determination of Antidepressant Efficacy of Commercial Hypericum perforatum Extracts Using a Learned Helplessness Paradigm, Joseph Davis
Department: Chemistry

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The Expression, Purification, and Oligomerization of Mutant sHSP 18-9 CTrl from Zea mays, Christine Marie English
Department: Chemistry

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Coenzyme B12: Finding the Smoking Gun, Anne Fischer
Department: Chemistry

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The Synthesis of Mixed-Multidentate Cobalt (3) Complexes, Ashley Fisher
Department: Chemistry

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Kinetic Analysis of Active Site-Arginine Mutants of Rabbit Muscle Creatine Kinase and of Glycocyamine as an Alternative Substitute for the Native Enzyme, Paul Geiss
Department: Chemistry

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The Characterization and Reduction of Methyl-alpha-(2-nitrobenzylidene)-acetoacetate to Synthesize 2-Methyl-3-carbomethoxyquinoline, Christopher Gulgas
Department: Chemistry

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Cholesterol Conjugated Antisense Oligonucleotide Uptake in Paramecium Tetraurelia, Nizar Palestine Hallak
Department: Chemistry

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The Preparation of a Catalytically Active Monomer of Rabbit Muscle Creatine Kinase by Site-Directed Mutagenesis and Gel Filtration Chromatography, Andrea Jorjorian
Department: Chemistry

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The Synthesis and Characterization of a Di-Substituted Quinoline Derivative Using an Iron Hydride Reagent, Candace Lovejoy
Department: Chemistry

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Bulky Molecules: A Computational Investigation of Halogenated Products, Meris Mandernach
Department: Chemistry

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ATPase Activities of Recombinant Rabbit Muscle Creatine Kinase and its N285A, N285D and N285Q Mutants, Guy Mulligan
Department: Chemistry

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Protein Determination of Maize Inbred Lines by Near-Infrared Spectroscopy, Jeffrey Munn
Department: Chemistry

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The Use of Solid Phase Microextraction for the Determination of Organochlorine Compounds in Soil Gas from the South Water Well Field of Wooster, Ohio, Eric Resnis
Department: Chemistry

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Expression and Purification of a SeMetHSP18-9, a Selenomethionine-Substituted Small Heat Shock Protein from Zea mays, Karen Robbins
Department: Chemistry

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The Synthesis of 1-(4-Mercaptophenyl)-1,1-di-(4-hydroxylphenyl) ethane (MDHE) Template Molecule for the Development of a Molecularly Imprinted Sol-Gel-Based Chemical Sensor for the Quantitation of DDT (1,1-Bis(4-chlorophenyl)-2,2,2-trichloroethane), Joshua Schaeffer
Department: Chemistry

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Measurement of Testosterone and pH as Biochemical Indicators of Stuttering, Heather Schieda
Department: Chemistry

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Determination of Bovine and Human Corneal Hydration Using Near-Infrared Spectroscopy, Kristin Silakoski
Department: Chemistry

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Determining the Presence of Petroleum Based Hydrocarbons in the Wooster Water Pollution Control Plant "Vacuator" Effluent, Amanda Lea Smeigh
Department: Chemistry

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Using Differential Scanning Calorimetry to Investigate a Possible Role for Arginine 214 of Rabbit Muscle creatine Kinase as a Structural Arginine, Sandra Tecklenburg
Department: Chemistry

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Understanding the Role of Structural Arginines: Determination of Secondary and Tertiary Structure Changes in R134 Creatine Kinase Mutants by FT-IR Spectroscopy, Adam Wegner
Department: Chemistry

Senior Independent Study Theses from 2000

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Quantification and Analysis of Protein Contaminants on Contact Lenses Using Near Infrared Spectroscopy, Benjamin Michael Arnold
Department: Chemistry

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The Quantitative Analysis of 1,1,1-Trichloroethane, 1,1,2-Trichloroethene, 1,1-Dichloroethane, and cis-1,2-Dichloroethene in Wooster City Groundwater, Denise Brown
Department: Chemistry

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The Oligomerization and Chaperone Activity of Small heat Shock protein 18-9 from Zea mays, Julie Buss
Department: Chemistry

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Computer Modeling of Anthroquinone Terminated Core-containing Polyamide Dendrimers, Dita Dobroshi
Department: Chemistry

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Determination of Nitrate Concentrations in Selected Surface Water Areas of Tuscarawas County, Ohio, Seth Duerr
Department: Chemistry

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The Cloning and the Transformation of the ORF Nucleotide Sequence of the 18-1 smHSP cDNA from Zea mays, Nicholas Brandon DuVall
Department: Chemistry

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Progress Toward the Determination of the Mechanism Responsible for the Sn1 Product Upon the Nucleophilic Attack of an Aziridinium Ion, Benjamin Gartrell
Department: Chemistry

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An Evaluation of Three Commonly Used Methods for the Determination of Nitrate Ion Concentration in Water Supplies, Ryan J. S. Kerr
Department: Chemistry

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An Ab Initio Investigation of the Internal Rotation of Ethane Derivatives, Jennifer A. Leete
Department: Chemistry

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An Ab Initio Investigation of Halogenated Cyclobutanes and Analogous Cyclopentenes, Jay M. MacGregor
Department: Chemistry

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Synthesis of 1,4-Diphosphoserinecyclohexane Compounds as Phospholipid Analog Components of the Phospholipid-Metal Ion Ternary-Complex, Crystal Lynn Mayle
Department: Chemistry

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Synthesis of cis- and trans- 1,3-cyclohexyl(bis)phosphoserine Compounds as Phospholipid Analogs of the Ternary Complex, Jessica Leigh Miller
Department: Chemistry

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Catalysis of Cis-Trans Isomerization in Quinoline Precursors, Brian K. Mirous
Department: Chemistry

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An Ab Initio Investigation into Pseudorotation in Cyclopentane, Smita Narayan
Department: Chemistry

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Reduction and Condensation of Nitro-Compounds to Quinolines Using an Iron Reagent, William Nethero
Department: Chemistry

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Potential Environmental Contamination by Coking Residues with an Emphasis on Polynuclear Aromatic Hydrocarbons, Jennifer Penrod
Department: Chemistry

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Variation of Reaction Conditions In the Prediction of Azindinium Ion Chemistry, Kristy Schavolt
Department: Chemistry

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The High Performance Liquid Chromatographic Separation of Monosaccharides Present in a Marine Oligosaccharide, Michael P. Suszter
Department: Chemistry

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The Molecular Chaperone Function of SmHSP 18-9 from Zea Mays, Amy M. Tsacoumangos
Department: Chemistry

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Examination of the Structural Requirements for Functional Calmodulin and Paramecium tetraurelia: An attempt to Construct CaM NN, Mark Unroe
Department: Chemistry

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Characterization of Porous Bis (trimethoxysilylpropyl) amine (tri-MSPA) Sol-Gel Materials, Aleashia Siobhan Washington
Department: Chemistry

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The Synthesis and Characterization of (Cyclohexyl)-(CBZ-ser-Bzl) Phosphodiester, Jennifer White
Department: Chemistry

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Expression and Purification of a sHSP18-9, a Small Heat Shock Protein from Zea mays, Julie A. Zeller
Department: Chemistry

Senior Independent Study Theses from 1999

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A Computational Investigation of Hydrogen Bonding in the Formic Acid Dimer, Nicole Brinkmann
Department: Chemistry

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Synthesis and Characterization of Cyclohexyl Phosphoserine Compunds as Phospholipid Analogs of the Phospholipid-Metal Ion Binding Site, Jacob Carmany
Department: Chemistry

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The Investigation of the Nitrate Concentration in Surface Waters in Tuscarawas County, Ohio, Carrie Coutts
Department: Chemistry

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Olefin Hydrogenation Using a Cationic Ruthenium Catalyst, Jennifer Ferguson
Department: Chemistry

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An Analytical Comparison of Municipal Tap Water and Various Bottled Waters, Andrew Hamilton
Department: Chemistry

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An Examination of the Capabilities of Spartan and MacSpartan and the Interpretation of the High Pressure Spectrum of trans- 1,3-Bromochlorocyclobutane and the Low Temperature Spectrum of trans-1,3-Dibromocyclobutane Using ab initio Calculations, Farhan Hashim
Department: Chemistry

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The Binding to Tooth Enamel of Phospholipid Vesicles Containing Entrapped Oral Medication, Jason Holton
Department: Chemistry

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Nitrate-Nitrogen Concentrations in Surface Water of Selected Areas in Wayne County, Ohio, Laura Markley
Department: Chemistry

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The Effects of Local Population and Brook Height on the Nitrogen and Phosphorus Concentrations in Addams Brook(NY) During the Course of the Summer Vacation Season, Sarah Mengers
Department: Chemistry

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Examination and Detection of Drug Samples Using Microscopic Fourier-Transform Infrared Spectroscopy, Krystal Louise Mohn
Department: Chemistry

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The Identification of Aldehydes as Their 2,4-Dinitrophenylhydrazone Derivatives by High Performance Liquid Chromatography, Using Personal Aldehyde Monitors and Air Cartridge Tubes as Sampling Techniques., Bradley Pierce
Department: Chemistry

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Use of Attenuated Total Reflectance Infrared Spectroscopy in the Analysis of Polymeric Degredation, Brenten D. Robson
Department: Chemistry

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The Isolation and Characterization of Fire Ant Antifeedants from Florida Betony, Andrew Schaeffer
Department: Chemistry

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Investigation of Catalytic Hydrogenation and Isomerization Using [(COD)Ru(CH2Cl2)2(PPh3)2][BF4]2, Jill Schieda
Department: Chemistry

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An Ab Initio Investigation into the Puckering of Cyclobutanes, C. Elliot Strimbu
Department: Chemistry

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Site-Directed Mutagenesis of Active Site Residues of Rabbit Muscle Creatine Kinase Using the Polymerase Chain Reaction, Michael Thomenius
Department: Chemistry

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Expression, Purification and Crystallization of a Small Heat Shock Protein from Maize, Douglas Weiser
Department: Chemistry

Senior Independent Study Theses from 1998

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Synthesis of Cis-1,2-Cyclohexyl Phosphatidylserine as a Small Molecule Analog Component of the Phospholipid-Metal Ion-Protein Ternary Complex, Sharon Austin
Department: Chemistry

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Synthesis of Highly-Functionalized Quinoline Derivatives Using Hydridotetracarbonylferrate (0) Monoanion as a Highly Selective Reducing Agent, Melissa Cerny
Department: Chemistry

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Clarification of Rate Constants of N-Heterocyclic Ligands in Pentacyanoferrtae (2) Complexes, Matthew Clapham
Department: Chemistry

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Tracking the Fates of Pentane Extractable Compounds Through the Wooster Sewage Treatment Plant, Michael Dean
Department: Chemistry