The full text of Senior Independent Study Theses submitted during and after 2012 are available to download only by College of Wooster users. Unless listed as an exemplar, all other theses are restricted.

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Senior Independent Study Theses from 2017

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Development of Mesoionic Carbene Ligands Containing Hydrogen-Bonding Functionalities for the Metal-Catalyzed Oxidative Coupling of Amines and Alcohols, Diego E. Arellano
Department: Chemistry

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Real-Time PCR Analysis of a Salt Stress Responsive LncRNA in Arabidopsis under Salt Stress Conditions, Peter J. Arts
Department: Biochemistry and Molecular Biology

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Improving p-XRF Capabilities for In Situ Geochemical Analysis: A Case Study of Arkansas's Magnet Cove and Stanley Shale, Elizabeth Backman
Department: Chemistry; Geology

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Characterizing Ribonucleotide Reductase's Role in Promoting Genomic Instability in tsa1Δ Mutants, Brianna L. Bauer
Department: Biochemistry and Molecular Biology

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Increasing Diversity in Chemistry and Environmental Education: Making Outdoor, Experiential Education more Accessible to High School Chemistry Teachers, Molly Dysis Billings
Department: Chemistry

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Mechanistic Investigation into the Liver Kinase β-1 – AMP-Activated Protein Kinase – Phosphagen Kinase Phosphorylation Cascade, Camille K. Boufford
Department: Biochemistry and Molecular Biology

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Investigating Changes in Protein Markers Following Sleep Deprivation in Drosophila Melanogaster, Petra N. Boutros
Department: Biochemistry and Molecular Biology; Neuroscience

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The Effect of pH on the Direct Photolysis of Warfarin in Aqueous Solution, Bailey B. Bowers
Department: Chemistry

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Effects of Metal Salts and Anoxia on the Photodegradation of Red Food Dyes, Catherine Boyles
Department: Chemistry

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Got Light? : A Study of the Physical Properties of Single-Layer Organic Light-Emitting Diode Devices Using a Poly(p-phenylene vinylene) Derivative, Harley Brandstadter
Department: Chemistry

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A genetic approach to examine how the Thioredoxin system influences genomic stability in S. cerevisiae, John Buchan
Department: Biochemistry and Molecular Biology

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Synthetic Progress Towards Regioselective Disulfide Bond Formation via Azide-Alkyne Cycloaddition, Zachary T. Buchan
Department: Chemistry

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Attempting to Identify the Calcium-Dependent Sodium Channel in Paramecium Tetraurelia, Thomas J. Camp
Department: Biochemistry and Molecular Biology; Neuroscience

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Determining the effects of polyadenylation on long noncoding RNA expression and stability in response to stress, Allyson Caselberry
Department: Biochemistry and Molecular Biology

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The Evaluation of Organosilica Sorbent Media for the Removal of Perfluoroalkyl Compounds from Drinking Water, Rachel M. Collins
Department: Chemistry

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Progress Towards the Diastereoselective Synthesis of Dipeptide Analogs via the Use of Chiral N-acylhydrazone Auxiliaries in the Ugi Reaction, Anna V. Davies
Department: Chemistry

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Evidence of Differential Expression in the Calcineurin Gene Family in Paramecium Tetraurelia And Science in Fiction is not always Science Fiction: An analysis of the German Vergangenheitsbewältigungsliteratur through a Science Fiction Lens as a means to discredit Nazi Racial Science, Alexander G. Day
Department: Biochemistry and Molecular Biology; German Studies

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Exploring The Molecular Function of cAMP and Phosphodiesterase PDE1C during Axon Pathfinding in Drosophila Melanogaster, Alexandra R. Elchert
Department: Biochemistry and Molecular Biology

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Identification of Catalytic Residues in the 3C-like Protease of Maize chlorotic dwarf virus, Anna Emmick
Department: Biochemistry and Molecular Biology

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Development of a Novel Method of Unrestricted Polypeptide Synthesis Utilizing a Salicylaldehyde Based Auxiliary Molecule, Jake Eshelman
Department: Biochemistry and Molecular Biology

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Exploration of Palladium Catalyzed Cross-Coupling for the Synthesis of an Electroluminescent Polymer Model Compound, Leandra Forte
Department: Chemistry

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Assessing the Effects of Recombinant AK Genes on the Growth and Development of Myxococcus xanthus, Mark A. Grady
Department: Biochemistry and Molecular Biology

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Elucidating the Mechanism of the Oxidative Decarboxylation of 6-Hydroxynicotinate by 6-Hydroxynicotinate 3-Monooxygenase (NicC) Through Kinetic Analysis, Jack H. Harrington
Department: Chemistry

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A Brief Survey of the Metallic Properties of Electric Guitar Strings and Their Effects on Sound, Stephen Hause
Department: Chemistry

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Novel Synthesis of Difluorene Bisintercalators via Direct Amidation Using Swellable Organically Modified Silica (SOMS) and Employment of the CAN1 Forward Mutation Assay to Assess Mutagenicity, Hannah M. Hicks
Department: Biochemistry and Molecular Biology; Environmental Studies

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Investigation of Esterification Reactions in Swellable Organically Modified Silica Towards the Synthesis of Polyethylene Terephthalate, Kirstin M. Holm
Department: Chemistry

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Investigating the Potential Genetic Causes of the Marbled Phenotype in the Betta splendens, Jennifer Hurtig
Department: Biochemistry and Molecular Biology

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A Versatile Esterification Methodology Using Swellable Organically Modified Silica (SOMS) as Nano-Ractors, Hannah K. Huston
Department: Chemistry

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The Drosophila melanogaster polyadenosine RNA binding protein, Nab2, is necessary for survival and neural development, in a model of intellectual disability., Michael Kahl
Department: Biochemistry and Molecular Biology; Neuroscience

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Chemical Education Research Project: Helping Elementary School Teachers Inspire Their Students to Continue Learning Chemistry, Gretchen Kallmeyer
Department: Chemistry

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The Effect of a His Tag on IclR Interactions with DNA and Ligands in Escherichia coli, Mara A. Kingscott
Department: Biochemistry and Molecular Biology

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The Need for a New Style of Assessment in Introductory Chemistry Courses, Christopher LeCompte
Department: Chemistry

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The Effects of Male-Produced Adipokinetic Hormone I on the Fertility of Female Aedes aegypti, Anna L. McGlade
Department: Biochemistry and Molecular Biology

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Investigation of the Heck Reaction for the Synthesis of a Model Light-Emitting Copolymer, Angelo J. Melari
Department: Chemistry

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Substrate Specificity of Horseradish Peroxidase for the Oxidation of Pharmaceutical Compounds, Lance Metsger
Department: Biochemistry and Molecular Biology; Chemistry

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Investigation of Antidepressant Load Reduction Following Tertiary Wastewater Disinfection Treatment, Rachel A. Mole
Department: Chemistry

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Incoherent Broadband Cavity Enhanced Absorption Spectroscopy: Improving Sensitivity while Studying Solvent Effects in Benzene, Ryan W. Ostendorf
Department: Chemistry

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The Efficacy of Osorb® as a Catalyst Replacement for Friedel-Crafts Acylation, Alex Pearson
Department: Chemistry

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The Effect of Matrix Composition on the Photodegradation of Acetaminophen, Jake W. Polster
Department: Chemistry

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Allelochemical Extraction from Soil Using Swellable Organically Modified Silica, Adrienne Reding
Department: Biochemistry and Molecular Biology

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Development of Ruthenium (II)-Mesoionic Carbene Complexes for Investigation of Secondary Coordination Sphere Interactions in Homogeneous Catalysis, Lindsay L. Robinson
Department: Chemistry

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Investigating the Impact of Substituent Positioning on the Photochemistry of meta and ortho Aminobenzoic Acid Derivatives, Haley A. Rossiter
Department: Chemistry

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Biophysical Characterization of the Cofactors in the NicAB Complex from Bacillus niacini, Laura A. Sherer
Department: Biochemistry and Molecular Biology

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Modeling the Commitment to Senescence Through Mitochondrial Fusion and Chromosomal Restructuring, Herbert Sizek
Department: Biochemistry and Molecular Biology

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Analyzing H7 as a Possible Structural Determinant of Negative Cooperativity within the Phosphagen Kinase Enzyme Family, Katie Stock
Department: Biochemistry and Molecular Biology

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Investigating the Relationship Between Self-Interaction and Function of the Viral Suppressor of RNAi Expressed by Maize Chlorotic Dwarf Virus, Ben R. Stromberg
Department: Biochemistry and Molecular Biology

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Genetic Engineering of the GFP Coding Region for Expression of Fusion Proteins in Saccharomyces cerevisiae, Jenna S. Taira
Department: Biochemistry and Molecular Biology

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Differentiation of Anthraquinone-based Dyes and Pigments using Fluorescence, Madeline Rui Thomas
Department: Chemistry

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Characterizing the genetic determinants of the nicotinic acid degradation pathway in Bacillus niacini, Tsun Ki Jerrick To
Department: Biochemistry and Molecular Biology

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Desorption of Menthol from Swellable Organically Modified Silica: A Potential for Extended Transdermal Delivery Application, Todd P. Ulmer
Department: Chemistry

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Insecticide Fungicide Interaction and Synergistic Toxicity in Honey Bees, Andrea H. Wade
Department: Biochemistry and Molecular Biology

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The Fate of Pharmaceuticals: The Effects of Humic Acid on Amoxicillin's Rate of Photodegradation, Michael R. Whitaker
Department: Chemistry

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Investigating The Genetic Basis Of Melanistic Betta splendens, Harrison P. Wooten
Department: Biochemistry and Molecular Biology

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Evaluation of Organosilica Sebum Control Ingredients, Yaoyin Xu
Department: Chemistry

Senior Independent Study Theses from 2016

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Stabilizing Redox-Responsive Protein Network Interactions with a Thiol-Reactive Cross-Linker, Kristin M. Allan
Department: Biochemistry and Molecular Biology

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Differential Expression of a Novel lncRNA (Na2) Aids in Arabidopsis thaliana Survival Under High Salinity Stress, Michael D. Andes
Department: Biochemistry and Molecular Biology

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Solvent Effects on the Quantum Efficiencies and UV-induced Photodegradation of PABA and Padimate-O, Preetom Borah
Department: Chemistry; Music

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Evaluation of Organosilica-Iron Composites as A Soil Amendment to Protect Against Pesticide Drift, Taylor M. Bowen
Department: Chemistry

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Cochineal: Connecting Chemistry and Religious Studies through the World of Art, Amanda Carmichael
Department: Chemistry; Religious Studies

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Biomimetic Adsorbents for the Removal of Microcystins from Water, Kimberly Anne Carter
Department: Chemistry

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License and Registration Please: The Development of an In-Field THC Detection Test Using a Hybrid-Bio-Inorganic Stationary Phase, Catherine Christian
Department: Chemistry

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An Investigation of Effective Methods to Form and Hydrolyze H-Phosphonate Diester Bonds for a Nucleophilic Acyl Substitution Reaction, Albert J. Darling
Department: Chemistry

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The Partial Characterization of a Monooxygenase in Bacillus niacini, Morgan A. Dasovich
Department: Biochemistry and Molecular Biology

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Analysis of Bioaccumulation and Sublethal Toxic Effects in Eisenia fetida, Lactuca sativa, and Arabidopsis thaliana Following Antidepressant Exposure, Rachael S. Davis
Department: Biochemistry and Molecular Biology

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Stimulating Encapsulated Fragrance Release by Malodor Absorption, Andrea Michelle DeMarsh
Department: Chemistry

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Got milk? An In-Depth Analysis of Community Water Fluoridation and a Chemical Investigation of Fluoridated Milk as an Alternative to Fluoridated Water, Shikha Dharia
Department: Biology; Chemistry; Interdepartmental

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Laying the Groundwork for Illuminating the Relationship Between Structure and Catalytic Efficiency in Phz O, a Phenazine Biosynthesis Enzyme, Leslie A. Doone
Department: Biochemistry and Molecular Biology

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Impact of medium, ambient environment, and surface on the UV-induced degradation of carmine lake, Erin Drake
Department: Chemistry

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Characterization of Long Non-Coding RNA Expression During Low Temperature Stress in Arabidopsis thaliana: Exploring the Implications of Targeting lncRNA for Improved Plant Growth, Ellyn Evans
Department: Biochemistry and Molecular Biology

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Evaluation of Polysilsesquioxane Materials as a Solid-State Electrolyte Matrix in Lithium-Ion Batteries, Jackson M. Fielder
Department: Chemistry

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The Elucidation of a Mechanism for Malonic Acid Photooxidation in Aqueous Solution, Nathan J. Gimble
Department: Chemistry

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Preliminary investigation of Caenorhabditis elegans arginine kinase phosphorylation by AMPK, Andrew H. Greene
Department: Biochemistry and Molecular Biology

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A Dynamical Systems Approach to Understanding Synergies Between Thyroid Cancer Mutations, Andrew R. Hamel
Department: Biochemistry and Molecular Biology

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Synthetic Progress Towards the Production of Hydroxymethyl and Mercaptomethyl Salicylaldehyde Derivatives for use in Protein Chemical Synthesis, Conner A. Hoelzel
Department: Biochemistry and Molecular Biology

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Progress Towards a Total Synthesis of Grandilodine C, Trevor Horst
Department: Chemistry

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Examination of Introductory Chemistry Education via Correlational Analysis of Student Performance and Psychological/Demographical Factors, Joshua K. Houtz
Department: Chemistry

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Development and Testing of the Sentinel Passive Samplers Designed for Integrative and Rapid Adsorption of Environmental Water Contaminants, Ellen A. Hudson-Heck
Department: Chemistry

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Investigating the Structural Features that Promote Peroxiredoxin-Sulfiredoxin Interactions in Yeast, Joseph E. Kelly
Department: Biochemistry and Molecular Biology

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Generation of a NicC Bordetella pertussis Mutant: Investigating the Relationship Between Nicotinic Acid Degradation and Virulence Modulation, Melia Kovach
Department: Biochemistry and Molecular Biology

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Attempted Identification of the Calcium-Dependent Sodium Channel Gene in Paramecium tetraurelia using RNAi, Gwendolyn Kuzmishin
Department: Biochemistry and Molecular Biology

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Attempted Synthesis of 2,3,6-Trihydroxypyridine and Characterization of the Putative Ring-Cleavage Enzyme in Bacillus niacini Nicotinate Catabolism, Nicholas P. Lesner
Department: Chemistry

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Molecular Basis for Suppression of Genomic Instability by a Conserved Peroxidase, Matthew A. Loberg
Department: Biochemistry and Molecular Biology

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Photodegradation of p-aminobenzoic acid in different ambient and pH environments and stabilization by antioxidants, Briana E. Marlatt
Department: Chemistry

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Investigation of the Functionality of the Nicotinic Acid Degradation Pathway of Bordetella pertussis as a Potential Treatment for Whooping Cough, Dylan L. McCreary
Department: Chemistry

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Transdermal Drug Delivery Using Organosilica Encapsulants, Elizabeth McInturf
Department: Chemistry

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Deciphering the Metal Dependency of Novel Nicotinic Acid Dehydrogenase from Bacillus niacini, Jessica A. Meek
Department: Biochemistry and Molecular Biology

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Examining Evolution of Substrate Specificity Using Taurocyamine Kinase, Huyen Thai Ngoc Nguyen
Department: Biochemistry and Molecular Biology

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Horseradish peroxidase entrapped in organically modified silica for the degradation of endocrine disrupting compounds in drinking water, Jonathan E. Nutt
Department: Biochemistry and Molecular Biology

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Horseradish Peroxidase Entrapped in Organically Modified Silica for the Degradation of Endocrine Disrupting Compounds in Drinking Water, Jonathan E. Nutt
Department: Biochemistry and Molecular Biology

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Identification of Genes Involved in Exoprotease Activity in Pseudomonas chlororaphis (14B11), Jennifer M. Pilat
Department: Biochemistry and Molecular Biology

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Exploring the Effects of Sleep Deprivation on Gene Expression in Drosophila Melanogaster, Kate M. Redding
Department: Biochemistry and Molecular Biology; Neuroscience

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Requirement of Nab2 RNA Binding in Drosophila melanogaster Nervous System Development, Fatima L. Rodriguez
Department: Biochemistry and Molecular Biology; Neuroscience

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Mechanistic Investigation of the Ugi Reaction and Evaluation of Diastereomeric Control via Chiral Isocyanides, Peter J. Rohweder
Department: Chemistry

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Investigating the proposed acid-base catalyzed mechanism for 6-hydroxynicotinate 3-monooxygenase (NicC)., Alvi N. Sakib
Department: Biochemistry and Molecular Biology

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The Effect of Solvent and Acceptor on Hydrogen Bonds Between Benzyl Alcohol - Aromatic Systems, Michael H. Schlueter
Department: Chemistry

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Synthesis of a potential phosphatidylserine Analog: cis-1,4-Cyclohexyldiphosphoserine, Traci A. Scott
Department: Chemistry

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Investigating the Targets of Plant Pathogen RXLR Effectors Through Hypersensitivity to Stress Conditions in Saccharomyces cerevisiae, Colleen Elizabeth Sells
Department: Biochemistry and Molecular Biology

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The Putative Regulatory Role of Hydrogen Cyanide in Ethylene Signaling and Biosynthesis in Arabidopsis seedlings and tomato fruit, Heather Skinner
Department: Biochemistry and Molecular Biology

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Enhancing the Bioavailibility of the Dietary Supplement Curcumin through Nanodispersions, Kevin B. Smith Jr
Department: Chemistry

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Synthesis of a Potential Phospholipid Analog: trans-1,4-cyclohexane-diphosphoserine, Abby Szlachta
Department: Chemistry